Prof. Dr. Stefan Endres

Top 10 Publications

From: Top Papers — Division of Clinical Pharmacology, LMU Klinikum

Members of the Division of Clinical Pharmacology are shown in bold; doctoral students are additionally underlined.

1. 

   Gottschlich A, Thomas M, Grünmeier R, Lesch S, Rohrbacher L, Igl V, Briukhovetska D, Benmebarek MR, Vick B, Dede S, Müller K, Xu T, Dhoqina D, Märkl F, Robinson S, Sendelhofert A, Schulz H, Umut Ö, Kavaka V, Tsiverioti Ch, Carlini E, Nandi S, Strzalkowski T, Lorenzini T, Stock S, Müller P, Dörr J, Seifert M, Cadilha B, Brabenec R, Röder N, Rataj F, Nüesch M, Modemann F, Wellbrock J, Fiedler W, Kellner Ch, Beltrán E, Herold T, Paquet D, Jeremias I, von Baumgarten L, Endres S, Subklewe M, Marr C, Kobold S.

   Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.

   Nature Biotechnology 2023; 2023 Mar 13. JIF²⁰²¹ 68.2. PubMed

2. 

   Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou A, Schuebel M, Jobst J, Zhang T, Doerr J, Mearkl F, Majed L, Meuller PJ, May P, Gottschlich A, Tokarew N, Leucke J, Oener A, Schwerdtfeger M, Andreu-Sanz D, Gruenmeier R, Seifert M, Michaelides S, Hristov M, Koenig LM, Cadilha B, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell R, Cerezo-Wallis D, Tejedo C, Soengas M, Bald T, Huber S, Endres S, Kobold S.

   T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.

   Immunity 2023; 143-161.e11. JIF²⁰²¹ 43.5. PubMed

3. 

   Boehmer D, Formisano S, de Oliveira Mann C, Mueller S, Kluge M, Metzger P, Rohlfs M, Hörth Ch, Kocheise L, Lichtenthaler S, Hopfner KP, Endres S, Rothenfusser S, Friedel C, Duewell P, Schnurr* M, Koenig* L.

   OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis.

   Science Immunology 2021; 61, eabe2550. JIF²⁰²¹ 30.6. Science Immunology, Press Release

4. 

   Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha B, Dantes Z, Rataj F, Dorman K, Lutz J, Karches C, Heise C, Kurzay M, Larimer B, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth Ch, Benmebarek MR, Dhoqina D, Gruenmeier R, Seifert M, Oener A, Umut Ö, . . . Rothenfusser S, Duewell P, Koenig L, Schnurr M, Subklewe M, Liss A, Halama N, Reichert M, Mempel T, Endres S, Kobold S.

   T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.

   Nature Biomedical Engineering 2021; 35:2243-2257. JIF²⁰²⁰ 29.2. Nature BME, Press Release

5. 

   Kobold* S, Grassmann* S, Chaloupka M, Lampert C, Wenk S, Kraus F, Rapp M, Duewell P, Zeng Y, Schmollinger J, Schnurr M, Endres S#, Rothenfußer S#.

   Impact of a new fusion receptor on PD-1-mediated immunosuppression in adoptive T cell therapy.

   The Journal of the National Cancer Institute 2015; 107. JIF²⁰¹⁵ 15.2.

6. 

   Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, Zeng Y, Chmielewski M, Schmollinger J, Schnurr M, Rothenfußer S, Schendel DJ, Abken H, Sustmann C, Niederfellner CG, Klein C, Bourquin C, Endres S.

   Selective bispecific T cell recruiting antibody enhances anti-tumor activity of adoptive T cell transfer.

   The Journal of the National Cancer Institute 2015; 107:364. JIF²⁰¹⁵ 15.2.

7. 

   Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J.

   Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.

   Nature Immunology 2010; 11:63-9. JIF²⁰¹⁰ 26.2.

8. 

   Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlaeger N, Endres S, Tardivel A, Tschopp J, Ruland J.

   Syk kinase signaling couples to the Nalp3 inflammasome for anti-fungal host defense.

   Nature 2009; 459:433-6. JIF²⁰⁰⁹ 38.6.

9. 

   Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G.

   5' triphosphate RNA is the ligand for RIG-I.

   Science 2006; 314:994-997. JIF²⁰⁰⁶ 35.3.

10. 

    Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, Noronha A, Manoharan M, Akira S, de Fougerolles A, Endres S, Hartmann G.

    Sequence-specific potent induction of IFN-a by short interfering RNA in plasmacytoid dendritic cells through TLR7.

    Nature Medicine 2005; 11:263-70. JIF²⁰⁰⁵ 30.6.

All Publications

Full list on PubMed: Link

Patents

(sorted by filing date)

1. PD-1-CD28 fusion proteins and use thereof in medicine.

   Inventors: Sebastian Kobold, Stefan Endres · Applicant: Stefan Endres, Sebastian Kobold

   WO EP US CN JP AU CA DK ES FI HU PL PT JP2024073636A
   Priority 2015-06-19 · Filed 2024-03-21 · Published 2024-05-29

2. Anti-CD86 CAR expressing lymphocytes for targeted tumor therapy.

   Inventors: Sebastian Kobold, Adrian Gottschlich, Ruth Grünmeier, Stefan Endres, Carsten Marr, Moritz Thomas · Applicant: Ludwig-Maximilians-Universität München, Helmholtz Zentrum München

   WO WO2024160845A1
   Priority 2023-01-30 · Filed 2024-01-30 · Published 2024-08-08

3. Anti-CSF1R CAR expressing lymphocytes for targeted tumor therapy.

   Inventors: Stefan Endres, Adrian Gottschlich, Sebastian Kobold, Stefanie Lesch · Applicant: Ludwig-Maximilians-Universität München

   WO EP AU CA AU2022327766A1
   Priority 2021-08-13 · Filed 2022-08-12 · Published 2023-12-14

4. Improved adoptive T-cell therapy.

   Inventors: Christian Klein, Claudio Sustmann, Gerhard Niederfellner, Martina Geiger, Stefan Endres, Sebastian Kobold · Applicant: F. Hoffmann-La Roche AG, Ludwig-Maximilians-Universität München

   WO EP US CN JP KR AU BR CA IL MX JP2022169543A
   Priority 2016-06-30 · Filed 2022-07-29 · Published 2022-11-09

5. CXCR6-transduced T cells for targeted tumor therapy.

   Inventors: Stefan Endres, Simon Grassmann, Sebastian Kobold, Moritz Rapp · Applicant: Ludwig-Maximilians-Universität München

   WO EP US JP AU CA DK ES AU2022205240A1
   Priority 2015-10-16 · Filed 2022-07-14 · Published 2022-09-29

6. Bispecific antibody molecules with antigen-transfected T-cells and their use in medicine.

   Inventors: Carole Bourquin, Raffaella Castoldi, Stefan Endres, Christian Klein, Sebastian Kobold, Gerhard Niederfellner, Claudio Sustmann · Applicant: Ludwig-Maximilians-Universität München, Hoffmann-La Roche Inc.

   WO EP US CN JP KR BR CA HK MX RU US11732052B2
   Priority 2012-02-03 · Filed 2020-04-02 · Granted 2023-08-22 · Published 2023-08-22

7. CCR8 expressing lymphocytes for targeted tumor therapy.

   Inventors: Bruno Cadilha, Stefan Endres, Sebastian Kobold · Applicant: Klinikum der Universität München

   WO EP US AU CA AU2020237633A1
   Priority 2019-03-08 · Filed 2020-03-06 · Published 2021-08-05

8. Composition and method for inducing immune response in mammal and method of treatment.

   Inventors: Gunther Hartmann, Veit Hornung, Stefan Endres, Antonin de Fougerolles · Applicant: Alnylam Pharmaceuticals Inc.

   WO EP US JP AU CA JP2012031191A
   Priority 2004-12-09 · Filed 2011-10-05 · Published 2012-02-16

9. Compositions and methods for inducing an immune response in a mammal and methods of avoiding an immune response to oligonucleotide agents such as short interfering RNAs.

   Inventors: Antonin de Fougerolles, Stefan Endres, Gunther Hartmann, Veit Hornung · Applicant: Alnylam Pharmaceuticals, Inc.

   AU AU2011203218A1
   Priority 2004-12-09 · Filed 2011-06-30 · Published 2011-07-21

10. Immunotherapy of chronic infections and of malignant diseases.

    Inventors: Stefan Endres · Applicant: Stefan Endres

    EP US US20030228278A1
    Priority 2002-06-10 · Filed 2003-06-09 · Published 2003-12-11

Link to Google Patents search:

• Google Patents search

CV

Full CV Downloads

• CV (German)
• CV (English)

Biomedicine Pearls

• Style Guide: How to format a scientific text
• Mnemonic for aetiology (German: „Ätiologie kommt aus dem Ei“ — “aetiology comes from the egg”)
  • E – entzündlich (inflammatory) or I – infektiös (infectious)
  • M – maligne (malignant) or M – metabolisch (metabolic)
  • T – traumatisch (traumatic) or V – vaskulär (vascular)
  • P – psychogen (psychogenic) and others
• Medical specialties (German postgraduate training regulations)

Other Pearls

• Ten favorite pics

Links — Medicine

• Division of Clinical Pharmacology, LMU University Hospital, LMU Munich
• LinkedIn (Stefan Endres)

Links — Beyond Medicine

Favorite Songs

• Dekker: Celebrate the small things
• Shawn Mendez, Capitol Hill, I can treat you better

Favorite YouTube Science Videos

• Polymerase in action
• Scleroderma etc. (Townsend Teaching)

Favorite Photos

Guestbook